TDD line for hearing impaired: 303-691-770, CO HELP (general covid questions): 303-389-1687 or (877) 462-2911, 211 Colorado (vital covid resources): 2-1-1 or (866) 760-6489 or text your zip code to 898-211, Colorado Crisis Services: 1-844-493-8255 or trext TALK to 38255. When both of these substances are found in drinking water, the combined levels should be compared with the health advisory level of 70 ppt. ?���:��0�FB�x$ !���i@ڐ���H���[EE1PL���⢖�V�6��QP��>�U�(j J Occup Environ Med 40(7):614–622, Toft G, Jonsson BA, Lindh CH et al (2012) Exposure to perfluorinated compounds and human semen quality in arctic and european populations [J]. pp 145-164 | As new studies become available, our understanding of the health impacts of these chemicals in humans will continue to grow. Therefore, it is necessary to study health effects of various PFCs and their alternatives, and analyze the different environmental behaviors of isomers and homologues of PFCs. Research has … Almost everyone has detectable levels of PFOS, PFOA, and other PFCs in their blood. SE El Paso County Preliminary Assessment of Cancer and Birth Outcomes  (06/30/16). In a highly exposed community living near a chemical plant, PFOS and PFOA have been associated with pre-eclampsia (pregnancy-induced hypertension), birth defects (PFOA only), and increased uric acid levels – a marker of heart disease. Research suggests that high levels of certain PFAS chemicals, including PFOA and PFOS may: Increase cholesterol levels. Environ Sci Technol 51(11):6342–6351, Gsh (2015) Globally harmonized system of classification and labelling of chemicals(ghs).First revised edition. Increase the risk of serious conditions like high blood pressure or pre-eclampsia in pregnant women. Chemosphere 220:866–882, Robel AE, Marshall K, Dickinson M et al (2017) Closing the mass balance on fluorine on papers and textiles [J]. Perfluorocarbons are not toxic, and there are no direct health effects associated with exposures to them. In the event that a person is exposed to PFAS chemicals, there are a variety of factors that influence the potential for health effects. These health effects include altered metabolism, 3 fertility, 4 reduced fetal growth and increased risk of being overweight or obese, 5 and reduced ability of the immune system to fight infections… However, most of these studies analyzed only a small number of PFAS chemicals, and not all of them have the same health effects. The structure and physicochemical properties of PFCs can greatly affect their environmental behaviors and the safety of emerging perfluorobutane sulfonates (PFBS) and other substances cannot be ignored. Increase the risk of an asthma diagnosis. These animal studies have found that PFAS can cause damage to the liver and the immune system. Environ Health Perspect 118(8):1100–1108, Kennedy GL, Butenhoff JL, Olsen GW et al (2004) The toxicology of perfluorooctanoate[J]. Environ Res 154:145–151, Hu XDC, Dassuncao C, Zhang XM et al (2018) Can profiles of poly- and perfluoroalkyl substances (pfass) in human serum provide information on major exposure sources? Chemosphere 83(10):1320–1325, Barzen-Hanson KA, Field JA (2015) Discovery and implications of c-2 and c-3 perfluoroalkyl sulfonates in aqueous film-forming foams and groundwater [J]. Additional research may change our understanding of the relationship between exposure to PFAS and human health effects. Cite as. Serum PFOS levels have also increased exponentially in some areas of China over the past few years, likely reflecting increased PFOS production in China. Scientists are actively studying the health impacts of exposure to PFAS chemicals at levels and mixtures similar to those seen in Colorado. 28.8 Perfluorinated Compounds. stream 3 0 obj Ecotoxicol Environ Saf 149:88–95, Paustenbach DJ, Panko JM, Scott PK et al (2007) A methodology for estimating human exposure to perfluorooctanoic acid (pfoa): a retrospective exposure assessment of a community (1951-2003) [J]. Research Triangle Park, NC: National Toxicology Program. Humans are exposed to many chemicals in addition to PFCs. %PDF-1.7 J Toxicol Environ Health-Part A-Curr Issues 70(1):28–57, Skutlarek D, Exner M, Farber H (2006) Perfluorinated surfactants in surface and drinking waters [J]. Anal Chim Acta 619(2):221–230, Murakami M, Shinohara H, Takada H (2009) Evaluation of wastewater and street runoff as sources of perfluorinated surfactants (pfss) [J]. 2 0 obj Few human health studies of PFCs have been conducted in the general population. x���wTS��Ͻ7�P����khRH �H�. Colorado Health Information Data Set (CoHID), Local Pubic Health and Environment Resources, Air Quality - Monitoring, Modeling and Data, Perfluorinated compounds - health recommendations, Coronavirus Disease 2019 (COVID-19) in Colorado: State & National Resources, Toxicology and environmental epidemiology, Perfluorinated compounds in drinking water, water treated by a reverse osmosis system, SE El Paso County Preliminary Assessment of Cancer and Birth Outcomes, Addendum to SE El Paso County Preliminary Assessment of Cancer and Birth Outcomes.

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